Research Translation Core

Dr. Keith Pezzoli, Core Leader

Keith Pezzoli, Ph.D.
Urban Studies and Planning Program, 0517
University of California, San Diego
9500 Gilman Drive La Jolla, CA 92093-0517

phone: 858-534-3691
fax: 858-534-1691
e-mail: kpezzoli@ucsd.edu
web: http://regionalworkbench.org
   

Applying toxicogenomics and biomolecular technologies to environmental monitoring, risk assessment and bioremediation

Research Translation Core Brochure (627k pdf)
Research Translation Core Poster (2.6m pdf)

Research Translation Core proposal text (pdf file, 1.8m)
Research Translation Core
letters of support (pdf file, 21.0m)
SBRP presentation by Pezzoli, Marciano and Pellow (ppt file, big file: 22m)

3 required
components

SBRP network
SBRP science
SBRP org
chart
Research Translation
Core
Aims and
activities
A selection of images from the proposal, click thumnail for larger version.

Research Translation Core

Abstract
The Research Translation Core (RTC) of UC San Diego's Superfund Basic Research Program (SBRP) has four specific aims: (1) Build partnerships with government agencies and Tribal science labs to advance the practical contributions of toxicogenomics in environmental policy and planning; (2) Evaluate the utility of molecular biomarkers/biosensors, microtechnologies and bioremediation as new biological models/methods for improving environmental monitoring, risk assessment and remediation; (3) Organize technology showcases, entrepreneurs/innovators forums and educational workshops to foster the commercial development and utilization of innovative SBRP technologies; and (4) Communicate complex research findings to broad audiences through periodic workshops; symposia; participation in regional, national and international conferences; publications, and Web-based systems. The broad long-term objective is to apply toxicogenomic knowledge and biomolecular technologies to real-life problems concerning hazardous substances and environmental health. Along these lines, biomarkers developed by SBRP scientists will be evaluated, in partnership with the San Diego Baykeeper, Tribal labs and government agencies responsible for water quality monitoring, as potentially effective new cellular and analytic tools for detecting Superfund toxicants in contaminated watersheds. At the same time, SBRP-industry partnerships will promote the experimental development and commercialization of novel bioremediation technologies (e.g., transgenic plants that can hyper-accumulate heavy metals out of contaminated soil), and microtechnologies (e.g., labs-on-a-chip that can be used as biosensors for detecting exposure to pesticides). The RTC’s approach leverages strong working partnerships and information/visualization technologies already developed by the Regional Workbench Consortium (RWBC) in partnership with the San Diego Supercomputer Center. The RWBC was established as part of UCSDs SRRP Outreach Core (2000-2005); it is a Web-based research and learning network for sustainable development. The RTC’s toolkit includes on-line geographic information systems (GIS), decision support systems (DSS), multimedia interactive stories, and 3D visualization.

Resources and Links:  
   

Regional Workbench:
http://regionalworkbench.org
A collaborative, web-based network of researchers and community partners dedicated to creating knowledge and linking that knowledge to action for sustainable development.

Sept 20-24, 2004: A group of RWBC leaders presented an invited "Special Focus Session" at the EPA's Monitoring Science and Technology Symposium in Denver, Colorado. The RWBC presentation focused on " Linking Science & Technology to Policy & Planning for Sustainable City-Region Development."

  • The Regional Workbench Consortium (RWBC): The Role of Research Universities in Enabling Sustainable City-Region Development, Keith Pezzoli
  • Community Holistic Interactive Mapping Environment (Chime) for Analysis and Visualization of Regional Superfund Toxicants Data, Ilya Zaslavsky
  • Building Watershed-Scale Information Systems and Partnerships for Integrated Ecological Planning, Environmental Mitigation and River Park Conservation, Richard Marciano
  • San Diego Baykeeper Binational Water Quality Monitoring Program, Hiram Sarabia

For a summary of the above listed presentations, click here (pdf file)

Web-Based Interactive Mapping - allows the user to access and visualize updated environmental data including sources of toxins, biodiversity monitoring and management, and land use and jurisdiction.

Superfund history and presentation on evaluation methods for research translation, click here (14m pdf file)

Region 9 Newsletters

Mike Gill, editor
ORD Hazardous Substances Technical Liaison
US EPA Region 9 / SFD-84
75 Hawthorne Street
San Francisco, CA  94105
415-972-3054
415-947-3520 (Fax)
Gill.Michael@epa.gov

OFFICE OF RESEARCH AND DEVELOPMENT (ORD) HAZARDOUS SUBSTANCES TECHNICAL LIAISON
REGION 9 NEWSLETTER Winter 2006 Edition, No. 34